EvE Online is attractive to me in many ways, but as far as I'm concerned, its glaring flaw is that it doesn't use physical laws to define parameters and create diverse situations or use any part of cosmology to inspire its content. Every single palpable or use-able thing in EvE Online is man-made.
Infinity is as close a successor as I've seen to the most impressive technical game I've ever played: Frontier; Elite II, which simulated the laws of gravity, solar system orbits, it even had stars as big as 100 suns.
CCP could do much worse than take note.
Infinity; The Quest for Earth (official site)